Yes, The Coalition for Epidemic Preparedness Innovations (CEPI) is inviting applications for the Broadly Protective Vaccine Against New Emerging Variants and Variants of Concern of SARS-CoV-2 Virus (BPCoV2) to prevent disease caused by circulating SARSCOV-2 variants of concern and emergent variants of interest (in aggregate referred to as ‘variants’ herein).
The main objective of the first part of this call for applications is to support the research and development of broadly protective SARS-CoV-2 vaccines (BPCoV2) to meet the need for protection against variants. Emphasis is again on antigen design to elicit durable, potent and broad protection against variants. Both novel Spike antigens and other relevant viral antigens will be considered.
The TPP for a BPCoV2 vaccine should aim for the following indication(s): active immunization of at-risk individuals who remain susceptible to moderate-to-severe disease and mortality caused by variants, regardless of prior SARS-CoV-2 vaccination status; used in a primary vaccination series, or as a booster following primary vaccination against ancestral strains of SARS-CoV-2, to prevent disease and mortality, and ideally to prevent infection and viral transmission. Such vaccines may also be used as a booster following clinical recovery from disease due to ancestral SARS-CoV-2 in high-risk individuals, based on specific risk factors. In the long term: active immunization of at-risk persons to prevent disease and infection.
The deadline to submit applications for this program is 31-May-21.
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